400

Application of chemical principles to chemical and environmental processes. Topics include mass and energy balances over complex systems, reaction kinetics and thermodynamics, combustion, behavior of real gases, and waste minimization. Directed toward students with career interests in industry and/or chemical or environmental engineering.

Introduction to the chemistry of transition metal organometallics. Descriptions of the bonding, synthesis, structures, and reactions of major classes of organometallic compounds, as well as their role in organic synthesis and catalysis.

The discussion of certain types of reactions for the synthesis of compounds having significance to organic or bioorganic chemistry. Examples include addition/elimination; oxidation/reduction; free radical; carbanionic; pericyclic; and other types of reactions.

Detailed studies of the use of modern instrumental methods for the analysis of organic, inorganic, and biochemical samples. Emphasis on nuclear magnetic resonance, mass, infrared, and electronic spectroscopies.

The course introduces students to the drug discovery and development process with a focus on how organic chemistry is involved in that process. Students learn how drugs are developed and targeted towards different receptors/enzymes and how they interact with those receptors/enzymes. In addition, students learn about drug metabolism and time is spent focusing more closely on specific classes of drugs such as anticancer, antibacterial and antiviral agents.

An overview of polymers, with an emphasis on their chemistry, properties, and significance. Focus on the synthesis, characterization, and fabrication, and physical chemistry of polymers.

Topics include introduction to molecular symmetry and group theory. Discussions of electronic structure of atoms and their periodic properties followed by detailed considerations of ionic and covalent bonding. Acid-base theories presented in addition to general chemistry of the elements with emphasis on transition metals. Introduction to organometallic chemistry and bio-inorganic chemistry included.

State-of-the art biochemical and molecular techniques are taught within the hands-on, laboratory-based course. Potential topics include the polymerase chain reaction (PCR), oligonucleotide synthesis, DNA/protein sequencing and analysis (BLAST, DNASIS), pulse-field gel electrophoresis, gas chromatography-mass spectroscopy (GC-MS), nuclear magnetic resonance (NMR) spectroscopy, high performance liquid chromatography (HPLC), immunochemistry, and/or other contemporary techniques. Minimum of 2 credits of this course.

Laboratory studies of inorganic and organometallic compounds and ions. Synthetic experiments require inert atmosphere (vacuum line, dry box, and Schlenk) techniques; characterization by spectral, solid-state, and electrochemical methods. One laboratory period per week.

Explores the interrelationships of chemistry within the aquatic environment. Topics will include (1) energy flow and transformations, (2) chemical cycles in the environment, (3) fate and transport of chemical in surface and subsurface water, soil, and air, (4) aquatic chemistry, including the carbon dioxide cycle, precipitation reactions, complexation reactions, and redox chemistry, (5) phase interactions, (6) aquatic microbial biochemistry, (7) water pollution, and (8) water treatment.

Introduces the chemistry occurring within both natural and polluted atmospheres, with an emphasis on fundamental principles. Topics include: gas-phase chemistry, aerosol formation and heterogeneous chemistry, meteorology, and current environmental issues (ozone holes, global warming, etc.). Class activities will include discussions of technical papers drawn from contemporary scientific literature and simulations of environmental problems through computer models.

A continuation of BIOL 333, the course explores biochemical concepts and pathways with an emphasis on problem solving. Cellular control and coordination of biochemical pathways is emphasized in light of an advanced understanding of protein biochemistry. Lecture only.

Topics of special or current interest offered periodically.

Topics of special interest. Non-laboratory workin association with faculty supervisor. May require course prerequisites as determined by instructor.

For students having senior standing. Study and research areas include analytical, inorganic, organic, physical, and polymer chemistry. Prerequisites depend upon areas of study and research.

For students having senior standing. Study and research areas include analytical, inorganic, organic, physical, and polymer chemistry. Prerequisites depend upon areas of study and research.

Topics of current research interest; presentations by seniors, graduate students, faculty, and visitors. Every student is required to present one seminar during one of the two semesters. Emphasis on detailed knowledge of subject matter, techniques for searching the professional literature, and procedures for the preparation and presentation of a professional seminar. Majors only.

Topics of current research interest; presentations by seniors, graduate students, faculty, and visitors. Every student is required to present one seminar during one of the two semesters. Emphasis on detailed knowledge of subject matter, techniques for searching the professional literature and procedures for the preparation and presentation of a professional seminar. Majors only

Students prepare oral presentations based on an assessment of current biochemical research papers. The course will help students to further develop critical reading and scientific communication skills. Faculty from both biology and chemistry participate in the seminar.

Preparation of an extensive written account of the student's original laboratory research including an in-depth literature survey, background discussion, presentation of data and results, and conclusions. Open to majors only.